Imitrex injections: how to use sumatriptan for fast migraine relief
Have a migraine that hits hard and fast? Imitrex (sumatriptan) injections can stop pain quickly for many people. This page gives plain, practical steps: when to use it, how to inject, safety checks, common side effects, and what to do if it doesn't work.
How to use Imitrex injections
Most adults use a 6 mg subcutaneous injection. If the first dose doesn't help after 1 hour, you can usually take a second 6 mg dose. Do not exceed 12 mg in 24 hours. Always follow your prescriber's instructions.
Using a pre-filled syringe or auto-injector is simple. Pick the thigh or upper arm, clean the skin with alcohol, pinch the area (if using a syringe), insert the needle at a 90° angle, and press the plunger. For auto-injectors, press firmly against the skin and hold for about 10 seconds so the full dose delivers. Afterward, dispose of the needle in a proper sharps container.
Inject as soon as you feel a migraine starting. The injection works faster than pills for many people. Don’t use it to prevent headaches or for tension-type headaches—this medicine is for acute migraine attacks.
Side effects, safety checks and alternatives
Common side effects include flushing, tingling, warmth, dizziness, and injection-site pain. Most of these pass quickly. Serious symptoms—chest tightness, severe shortness of breath, sudden weakness, slurred speech, or fainting—need emergency care right away.
You should not use Imitrex if you have uncontrolled high blood pressure, coronary artery disease, a history of stroke, or certain heart rhythm problems. Also avoid it with MAO inhibitors or within 24 hours of other triptans. Combining sumatriptan with SSRIs or SNRIs can raise the risk of serotonin syndrome—tell your prescriber about all medicines you take.
If you're pregnant, breastfeeding, or have liver disease, ask your doctor for specific advice. If injections cause frequent side effects or don’t work, there are alternatives: oral triptans, nasal sprays, preventive medications, and non-drug options like Botox or CGRP inhibitors. Your clinician can help pick the safest choice.
Store the injector in its original box, away from direct heat and moisture. Most products are fine at room temperature below 25°C; don’t freeze them. Check the leaflet for exact storage rules and the expiry date.
Buying Imitrex usually requires a prescription. If you order online, use a licensed pharmacy and verify credentials. Fake meds can be dangerous.
If you're unsure about dosing, interactions, or heart risk, ask your pharmacist or doctor before trying an injection. With the right checks and technique, Imitrex injections can be a fast, effective option when a migraine strikes hard.