Super Cialis (Dapoxetine, Tadalafil) vs. Other ED & PE Treatments - Full Comparison

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Ever wondered if the hype around Super Cialis (a combo of dapoxetine and tadalafil designed for both premature ejaculation and erectile dysfunction) lives up to the claims? In this guide we break down exactly how it stacks up against the most common alternatives, so you can decide whether it’s worth a try.
Quick Takeaways
- Super Cialis blends Dapoxetine a short‑acting SSRI for premature ejaculation with Tadalafil a long‑lasting PDE5 inhibitor for erectile dysfunction.
- Onset: 30‑45 minutes; Duration: up to 36 hours (thanks to tadalafil).
- Price per tablet is higher than generic tadalafil alone but lower than buying two separate prescriptions.
- Key competitors: Viagra (sildenafil), generic Cialis (tadalafil), Levitra (vardenafil), Stendra (avanafil) and Priligy (dapoxetine‑only).
- Best for men who need both PE control and an ED solution in a single pill.
What is Super Cialis?
Super Cialis is a prescription tablet that combines dapoxetine (30 mg) and tadalafil (10 mg) in one dose. The idea is simple: dapoxetine works on the serotonin pathway to delay ejaculation, while tadalafil relaxes smooth muscle in the penis to sustain an erection. The combo was first approved in the EU in 2022 and has since entered several Asian markets, where doctors report high satisfaction among patients who struggle with both conditions simultaneously.
How Does It Work?
Two mechanisms, one pill. Dapoxetine Dapoxetine acts as a selective serotonin reuptake inhibitor (SSRI) with a rapid onset and short half‑life, meaning it can be taken a few hours before sex without lingering side effects. Tadalafil Tadalafil inhibits the phosphodiesterase‑5 enzyme, allowing blood flow to remain high for up to 36 hours. When combined, the user gets delayed ejaculation and a reliable erection that can last throughout the intended activity window.

Main Alternatives on the Market
Below are the most widely prescribed options that address either erectile dysfunction, premature ejaculation, or both:
- Viagra contains sildenafil, works within 30‑60 minutes, lasts about 4‑6 hours.
- Cialis pure tadalafil (10 mg or 20 mg) with a 36‑hour window but no PE control.
- Levitra contains vardenafil, onset 25‑60 minutes, duration up to 5 hours.
- Stendra features avanafil, fastest onset (<15 minutes), lasts about 6 hours.
- Priligy dapoxetine‑only, taken 1‑3 hours before sex, no effect on erections.
- Generic combinations of dapoxetine + tadalafil (off‑label compounding).
Head‑to‑Head Comparison
Product | Active Ingredients | Dosage Form | Onset | Duration | Typical US Price* (USD) | Prescription? |
---|---|---|---|---|---|---|
Super Cialis | Dapoxetine 30 mg + Tadalafil 10 mg | Oral tablet | 30‑45 min | Up to 36 h (tadalafil) | $45 per tablet | Yes |
Viagra | Sildenafil 50 mg | Oral tablet | 30‑60 min | 4‑6 h | $30 per tablet | Yes |
Cialis (generic) | Tadalafil 10 mg | Oral tablet | 30‑45 min | Up to 36 h | $20 per tablet | Yes |
Levitra | Vardenafil 10 mg | Oral tablet | 25‑60 min | 4‑5 h | $28 per tablet | Yes |
Stendra | Avanafil 100 mg | Oral tablet | 15‑30 min | 6‑12 h | $35 per tablet | Yes |
Priligy | Dapoxetine 30 mg | Oral tablet | 1‑3 h | ~4 h (PE control only) | $15 per tablet | Yes |
*Prices are average retail costs in 2025 US market and may vary by insurance, pharmacy, or bulk discounts.

Pros and Cons of Super Cialis
- Pros:
- One‑pill solution for two problems - saves time and reduces pill burden.
- Long tadalafil window means spontaneity is possible even days after dosing.
- Dapoxetine’s rapid clearance minimizes side effects compared with traditional SSRIs.
- Cons:
- Higher cost than buying generic tadalafil alone.
- Potential drug‑drug interactions (e.g., nitrates, alpha‑blockers) affect both components.
- Not suitable for men who only need ED treatment; they pay for dapoxetine they don’t use.
Choosing the Right Option - Decision Checklist
- Do you experience premature ejaculation *and* occasional erectile difficulty? If yes, a combo like Super Cialis makes sense.
- Are you on any nitrate medication or have severe cardiovascular disease? Avoid any PDE5 inhibitor, including Super Cialis.
- Is cost a major factor? Compare the per‑tablet price of Super Cialis with buying generic tadalafil + dapoxetine separately.
- Do you need a fast onset (under 20 minutes)? Stendra or generic sildenafil may be better.
- Is a long window (24‑36 h) important for you? Tadalafil‑based options-Cialis or Super Cialis-are the only choices.
By walking through these points you can narrow down from a ten‑product list to the one that truly fits your lifestyle and health profile.
Frequently Asked Questions
Can I take Super Cialis with alcohol?
Moderate alcohol (1‑2 drinks) usually doesn’t cause problems, but heavy drinking can lower blood pressure and increase the risk of dizziness when combined with tadalafil.
How often can I use Super Cialis?
Because tadalafil stays in the system for up to 36 hours, most doctors recommend no more than one tablet per day. Dapoxetine should not be taken more than once every 24 hours.
Is Super Cialis safe for men over 65?
Age itself isn’t a contraindication, but older men often have cardiovascular issues that make any PDE5 inhibitor riskier. A doctor should review heart health before prescribing.
What side effects should I watch for?
Common: headache, flushing, nasal congestion, mild nausea. Dapoxetine can cause dizziness or light‑headedness. Seek medical help if you develop a painful erection lasting >4 hours.
Can I buy Super Cialis without a prescription?
No. Both tadalafil and dapoxetine are prescription‑only in the U.S. Online pharmacies that claim otherwise are likely operating illegally.
Armed with this information, you can have a focused conversation with your urologist or primary‑care doctor and decide if Super Cialis fits your needs.
Sebastian Green
October 21, 2025 AT 01:40Reading through the breakdown, I can see how the combo might help folks juggling both issues. It’s reassuring that the onset is fairly quick and the duration covers most spontaneous plans. Hope you find what works best for you.